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  • Case 12/2020

MDX: Foal, diaphragmatic hernia (congenital) with concurrent aplasia of the pericardium 

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Foal, congenital pleuroperitoneal diaphragmatic hernia and left pericardium aplasia. Image a: Lateral view of the coelomic cavities after removal of the left abdominal and thoracic walls; hypoplastic left lung (1); the ventral (2) and the dorsal (3) loop of the left ascending colon; the thoracically translocated (4) and the abdominally located (5) parts of the liver; the diaphragm and area of the dorsal diaphragmatic defect (dotted accolade); the cranial lobe of the right lung which migrated cranial to the heart (white *). Image b: Caudal view of the large diaphragmatic defect with round and bold margins (arrow head) which allows the partial migration of liver and bowel (black *) from the abdomen into the thorax; fibrous aspect of the transdiaphragmatic migrated liver lobe (1) (extraabdominal region) connected by the abdominally located liver (2) by a stalk which contained dilated blood vessels and fibrous connective tissue (white arrow). The white * indicates the caudal pole of the left kidney. Image c: Heart and intestinal loops in situ. The dorsal (1) and the ventral (2) loop of the left ascending colon with the pelvic flexure (black star); small intestine loops (3) in contact with the heart; abundant serous fluid from the fused pleural and pericardial cavities and the partially formed pericardium (arrow head); Image d: The heart and the severely hypoplastic left lung (1) after removal of the intestinal loops; the right lung (2) and the caudal vena cava (3); the arrow indicates the remaining pericardium. Image e: Visceral surface of the liver. The parts of the liver which were translocated in the thoracic cavity (white*) were severely enlarged and exhibited diffuse fibrosis; bar = 10 cm

  • Case 1/2021

MDX: Dog, Extensive left ventricular noncompaction, with severe dilation of the right atrium and endocardial fibroelastosis

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Foal, congenital pleuroperitoneal diaphragmatic hernia and left pericardium aplasia. Image a: Lateral view of the coelomic cavities after removal of the left abdominal and thoracic walls; hypoplastic left lung (1); the ventral (2) and the dorsal (3) loop of the left ascending colon; the thoracically translocated (4) and the abdominally located (5) parts of the liver; the diaphragm and area of the dorsal diaphragmatic defect (dotted accolade); the cranial lobe of the right lung which migrated cranial to the heart (white *). Image b: Caudal view of the large diaphragmatic defect with round and bold margins (arrow head) which allows the partial migration of liver and bowel (black *) from the abdomen into the thorax; fibrous aspect of the transdiaphragmatic migrated liver lobe (1) (extraabdominal region) connected by the abdominally located liver (2) by a stalk which contained dilated blood vessels and fibrous connective tissue (white arrow). The white * indicates the caudal pole of the left kidney. Image c: Heart and intestinal loops in situ. The dorsal (1) and the ventral (2) loop of the left ascending colon with the pelvic flexure (black star); small intestine loops (3) in contact with the heart; abundant serous fluid from the fused pleural and pericardial cavities and the partially formed pericardium (arrow head); Image d: The heart and the severely hypoplastic left lung (1) after removal of the intestinal loops; the right lung (2) and the caudal vena cava (3); the arrow indicates the remaining pericardium. Image e: Visceral surface of the liver. The parts of the liver which were translocated in the thoracic cavity (white*) were severely enlarged and exhibited diffuse fibrosis; bar = 10 cm

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Histopathologic features of the left ventricular free wall and interventricular septum (a, b) Left ventricular free wall: multiple papillary trabeculae with a broad basis, an increased basophilia and a thick fibrous endocardium. Note that the noncompacted layer is thicker than the compacted one. c Prominent subendocardial fibrosis (asterisk). d Detailed image of the demarked area from image B. The arrows indicate several well-delineated areas of dystrophic mineralization (CL, compacted layer; IVS, interventricular septum; LV, left ventricular free wall; NCL, non-compacted layer)

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